Sevelamer
Sevelamer is a non-calcium, non-metal phosphate binder. It binds to dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream and facilitating its excretion through feces. This helps manage hyperphosphatemia and reduces the risk of calcification in patients with end-stage renal disease.
Dosage by Body Weight
Take with meals as prescribed. Dosage is individualized and adjusted based on serum phosphorus levels. Tablets must be swallowed whole and not chewed, crushed, or broken.
- Body Weight
- Below 5 kg
- Dose
- Not routine / Safety not established
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy have not been established in infants and very low weight pediatric patients.
- Body Weight
- 5-7 kg
- Dose
- Highly individualized
- Frequency
- Three times daily with meals
- Tracking Notes
- Dosing in pediatric patients is based on body surface area or clinical response and must be determined by a pediatric nephrologist.
- Body Weight
- 8-10 kg
- Dose
- Highly individualized
- Frequency
- Three times daily with meals
- Tracking Notes
- Dosing in pediatric patients is based on body surface area or clinical response and must be determined by a pediatric nephrologist.
- Body Weight
- 11-15 kg
- Dose
- Highly individualized
- Frequency
- Three times daily with meals
- Tracking Notes
- Dosing in pediatric patients is based on body surface area or clinical response and must be determined by a pediatric nephrologist.
- Body Weight
- 16-20 kg
- Dose
- Highly individualized
- Frequency
- Three times daily with meals
- Tracking Notes
- Dosing in pediatric patients is based on body surface area or clinical response and must be determined by a pediatric nephrologist.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine / Safety not established | Use only if prescribed | Safety and efficacy have not been established in infants and very low weight pediatric patients. |
| 5-7 kg | Highly individualized | Three times daily with meals | Dosing in pediatric patients is based on body surface area or clinical response and must be determined by a pediatric nephrologist. |
| 8-10 kg | Highly individualized | Three times daily with meals | Dosing in pediatric patients is based on body surface area or clinical response and must be determined by a pediatric nephrologist. |
| 11-15 kg | Highly individualized | Three times daily with meals | Dosing in pediatric patients is based on body surface area or clinical response and must be determined by a pediatric nephrologist. |
| 16-20 kg | Highly individualized | Three times daily with meals | Dosing in pediatric patients is based on body surface area or clinical response and must be determined by a pediatric nephrologist. |
Formulation
Purpose
To lower high blood phosphorus (phosphate) levels in patients with chronic kidney disease who are on dialysis.
Generic Name
SevelamerBranded Drug Names
Sevelamer is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.